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Webinar 4: A sustainable Tiered-Approach Model for Fragrance Ingredient Risk Assessment


Learn how Research Institute for Fragrance Materials (RIFM), measures the toxicity of complex cocktail of formulations and supports regulatory decision-making.
April 8, 2022

This webinar is a part of the Webinar Series “Green Chemistry, what it means today for industry sectors” where industry leaders from different sectors share their innovations and experiences.

Fragrance materials are used in a wide variety of cosmetic and household products. A typical fragrance contains formulations with up to 300 different ingredients, making the accurate knowledge of these ingredients very important. 

The Research Institute for Fragrance Materials (RIFM) has been assessing the safety of fragrance ingredients in accordance with the most current, internationally accepted guidelines. Since 2014, it is using an updated set of criteria designed to incorporate the most current science while avoiding animal studies. Today the Expert Panel for Fragrance Safety has approved RIFM Safety Assessments for more than 1,780 ingredients covering over 85% of the volume used by the fragrance industry.

Learn how RIFM measures the toxicity of ingredients used in fragrance and how it supports regulatory decision-making; while avoiding the use of animal studies. Senior scientists Dr. Nikaeta Sadeker (Respiratory Toxicology) and Dr. Mihwa Na (Dermatotoxicology) will describe the unique fragrance ingredient risk assessment process developed by RIFM; which informs the IFRA (International Fragrance Association) Standards to support regulatory decision-making.

Here are the webinar recordings:

Dr. Nikaeta Sadekar, Sr. Scientist, Respiratory Toxicology at Research Institute for Fragrance Materials, Inc. (RIFM), leads the respiratory endpoint for safety assessment and research efforts at RIFM. She has been engaged in various collaborations across the scientific community to develop RIFM’s Respiratory Science. In this webinar, Dr. Sadekar will focus on the local respiratory toxicity endpoint and discuss some of the challenges faced during this research.

Dr. Mihwa Na, Sr. Scientist, Dermatotoxicology at Research Institute for Fragrance Materials, Inc. (RIFM), leads the skin sensitization endpoint at RIFM, to conduct risk assessment and research projects to address the potential of a fragrance material to induce skin sensitization. The focus of her research includes evaluation and application of non-animal methods for skin sensitization risk assessment.

Here is the Q&A session, where the speakers answered the participants questions.

Stay Tuned for our future webinars! If you want to know more about ViridisChem, contact us.


ViridisChem is a software company offering essential toxicity data and tools for companies to move towards sustainable product development.

We have the world’s most comprehensive toxicity database with over 90 million chemicals, and utilizing this data, our software tools provide toxicity analysis of chemicals, mixtures and formulations, and product development processes.